This distinguished lecture honors Britton Chance

Britton Chance (1913-2010) was a world leader in transforming theoretical science into useful biomedical and clinical applications. Among his pioneering contributions to fundamental biomedical science were his discovery of numerous enzyme-substrate compounds, World War II development of computers for Radar, the elucidation of the fundamental principles of control of bioenergetics and metabolism, the first human subject study using 31P NMR (phosphorous nuclear magnetic resonance) spectroscopy and more recently optical spectroscopy and imaging of human brain and breast. Through decades of scholarly mentorship of colleagues in disciplines ranging from mathematics to clinical medicine, he brought additional distinction to this University and multiplied its contributions to improving the human condition.

Professor Chance was Eldridge Reeves Johnson University Professor of Biophysics, Physical Chemistry and Radiologic Physics at Penn. He received his undergraduate degree from Penn’s Towne Scientific School in 1935 and doctoral degrees from both Penn and the University of Cambridge. He was a member of the National Academy of Sciences and of the Institute of Medicine and a Foreign Member of the Royal Society of London. Among very many other recognitions, he received the National Medal of Science, the Benjamin Franklin Medal from the American Philosophical Society, the Biological Physics Prize from the American Physical Society, and honorary degrees from the Karolinska Institut, the Medical College of Ohio at Toledo, Semmelweis University, Hahnemann Medical College and the Universities of Pennsylvania, Helsinki, Dusseldorf and Buenos Aires. In his honor, Huazhong University of Science and Technology named a major laboratory as the Britton Chance Center for Biomedical Photonics

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CBE Seminars & Events

Britton Chance Distinguished Lecture in Engineering and Medicine

Samir Mitragotri
Dr. David J. Mooney

Robert P. Pinkas Family Professor of Bioengineering,
School of Engineering and Applied Sciences,
Harvard University
Core Faculty Member,
Wyss Institute for Biologically Inspired Engineering,
Harvard University

"Building Immunity with Biomaterials"

Wednesday, December 7, 2016, 3:00 PM, Wu and Chen Auditorium, Levine Hall

Dysfunction of the immune system underlies many diseases. However, strategies to effectively program an immune response, and reprogram undesired responses, by manipulating a patient’s immune cells are at an early stage. We are creating biomaterials capable of concentrating, interrogating, and manipulating immune cells ex vivo and in the body by controlling, in space and time, the interaction of the immune cells with immunomodulatory agents.  The utility of this concept in the development of therapeutic cancer vaccines will be highlighted.

Speaker Biography:

Dr. David Mooney is the Pinkas Family Professor of Bioengineering in the Harvard School of Engineering and Applied Sciences, and a Core Faculty Member of the Wyss Institute. His laboratory designs biomaterials to make cell and protein therapies effective and practical approaches to treat disease.  His team created the first biomaterial-based, therapeutic cancer vaccine, currently in a clinical trial for melanoma. He is a member of the National Academy of Engineering, and the National Academy of Medicine.  He has won numerous awards, including the Clemson Award from the SFB, MERIT award from the NIH, Distinguished Scientist Award from the IADR, Phi Beta Kappa Prize for Excellence in Undergraduate Teaching, and the Everett Mendelsohn Excellence in Mentoring Award from Harvard College.  His inventions have been licensed by twelve companies, leading to commercialized products, and he is active on industrial scientific advisory boards.

Previous Britton Chance Distinguished Lecturers

1995 Lewis S. Edelheit, General Electric Company
1996   Douglas A. Lauffenburger, Massachusetts Institute of Technology

George Georgiou, University of Texas at Austin
1999 Jeffrey A. Hubbell, University of Zürich
2000 W. Mark Saltzman, Cornell University
2001 Chaitan S. Khosla, Stanford University
2002 Sangtae Kim, Lilly Research Laboratories
2003 Larry V. McIntire, Rice University
2004     Deborah E. Leckband, University of Illinois at Urbana-Champaign
2004 Stephen R. Quake, Stanford University
2005 Frances H. Arnold, California Institute of Technology
2006 Adam P. Arkin, University of California at Berkeley
2007 Kristi S. Anseth, University of Colorado at Boulder
2008 Jay D. Keasling, University of California at Berkeley

Mark E. Davis, California Institute of Technology


David A. Tirrell, California Institute of Technology


Frank S. Bates, University of Minnesota


Arup K. Chakraborty, Massachusetts Institute of Technology

2013 Melody A. Swartz, Ecole polytechnique federale de Lausanne

James C. Liao, University of California, Los Angeles
Samir Mitragotri, University of California, Santa Barbara