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| Engineers Use DNA to Make Crystals That Can Switch Configurations | |||
Beyond serving as the backbone of modern biology, DNA has come to be a molecule of great interest to engineers. John Crocker and Talid Sinno, both of CBE, have used DNA to make a crystal that can switch into a more stable configuration under the right temperature conditions, much like heat-treated steel. |
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| Diamond Lab Research Reveals That Clots Can Sense Blood Flow | |||
The disease atherosclerosis involves the build up of fatty tissue within arterial walls, creating unstable structures known as plaques. These plaques grow until they burst, rupturing the wall and causing the formation of a blood clot within the artery. New research from the Diamond Lab shows that clots forming under arterial-flow conditions have an unexpected ability to sense the surrounding blood moving over it. |
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| Engineers Develop Protein 'Passport' That Helps Nanoparticles Get Past Immune System | |||
The body's immune system exists to identify and destroy foreign objects, whether they are bacteria, viruses, flecks of dirt or splinters. Unfortunately, nanoparticles designed to deliver drugs and implanted devices like pacemakers or artificial joints are just as foreign and subject to the same response. Research led by Dennis Discher, CBE, provides a "passport" for such therapeutic devices, enabling them to get past the body’s security system. |
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| The Nano Guru | |||
| Films made of nanoparticles are a crucial component found in everything from lithium ion batteries and solar cells to the next generation of display devices and anti-fogging coatings for automobile windshields. One problem facing engineers is that cracks routinely form in nanoparticle films during formation, interfering with their ability to work properly. With the goal of developing stronger, tougher nanoparticle films, Daeyeon Lee recently reported a new method to tackle this problem. | |||
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The Department of Chemical and Biomolecular Engineering at the University of Pennsylvania School of Engineering and Applied Science is the oldest continuously operating degree-granting program in chemical engineering in the U.S. Learn more about this photo!
"I tell my children that I am working with bubbles and they think I have the best job in the world – which I do!" says Daeyeon Lee, Assistant Professor of CBE. By learning how to modify the air and water interface, Lee is able to make "perfect" bubbles that have potential to enhance biomedical imaging and ultrasound therapy. Learn more!
Crystals That Can Switch Configurations
John Crocker’s team has made a crystal that rearranges itself into a stronger, more stable configuration, all by changing the mix of DNA strands on the spheres' exterior.Check it out!
